CLASSICS IN TOTAL SYNTHESIS NICOLAOU PDF

Nicolaou , E. Sorensen K. Nicolaou - Winner of the Nemitsas Prize in Chemistry. This book is a must for every synthetic chemist. With didactic skill and clarity, K. Nicolaou and E.

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Nicolaou was born on July 5, in Karavas, Cyprus, where he attended school until the age of He then moved to Nicosia to attend the Pancyprian Gymnasiuum. In , he emigrated from Cyprus to England where he spent two years learning English and preparing to enter the university. His advanced studies in chemistry were carried out at the University of London B.

Sondheimer and P. In , he crossed the Atlantic to the United States and completed postdoctoral appointments at Columbia University —, Prof. Katz and Harvard University —, Prof. Corey after which he joined the faculty at the University of Pennsylvania, where he rose through the ranks to become the Rhodes-Thompson Professor of Chemistry.

In May , Dr. Nicolaou joined Rice University as the Harry C. He synthesized almost two hundred naturally occurring molecules and thousands of designed analogs—perhaps more than any other in the history of this discipline. This distinction is all the more impressive in that his accomplishments cover almost all-important classes of bioactive molecules, whether one classifies them by structure or activity. He was the first to synthesize Taxol, the clinically used antitumor drug.

Nicolaou developed the theme of practicing organic synthesis with method development and applying it to biology and medicine from the basic to the translational, thereby establishing a new paradigm for total synthesis of natural products. Thus, from its original purpose of confirming the structure of the natural product, the practice of total synthesis evolved to being a fine art, then placed on systematic scientific foundation through retrosynthetic analysis, and now as a means to enable biology and medicine—all along without losing its identity and self-advancement.

He holds 10 honorary degrees from universities around the world, including one from The University of Cyprus. He is the author or co-author of almost scientific articles, reviews, and book chapters, 67 patents, and five books, including the popular Classics in Total Synthesis co-authored with his student E.

Montagnon , Wiley-VCH. His dedication to chemical education is evidenced by his training of hundreds of graduate students and postdoctoral fellows and the hundreds of lectures he gave in more than 30 countries around the world. Molecules That Changed the World, K. Nicolaou and T.

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